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Article

A probabilistic model to predict clinical phenotypic traits from genome sequencing.

PLoS computational biology - 1 Sept 2014

Chen Yun-Ching, Douville Christopher, Wang Cheng, Niknafs Noushin, Yeo Grace, Beleva-Guthrie Violeta, Carter Hannah, Stenson Peter D, Cooper David N, Li Biao, Mooney Sean, Karchin Rachel

Abstract excerpt

Genetic screening is becoming possible on an unprecedented scale. However, its utility remains controversial. Although most variant genotypes cannot be easily interpreted, many individuals nevertheless attempt to interpret their genetic information. Initiatives such as the Personal Genome Project (PGP) and Illumina's Understand Your Genome are sequencing thousands of adults, collecting phenotypic information and...

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PMID: 25188385
DOI: 10.1371/journal.pcbi.1003825
PMCID: PMC4154636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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