Article
Null allele, allelic dropouts or rare sex detection in clonal organisms: simulations and application to real data sets of pathogenic microbes.
Parasites & vectors - 15 Jul 2014
Séré Modou, Kaboré Jacques, Jamonneau Vincent, Belem Adrien Marie Gaston, Ayala Francisco J, De Meeûs Thierry
Abstract excerpt
BACKGROUND: Pathogens and their vectors are organisms whose ecology is often only accessible through population genetics tools based on spatio-temporal variability of molecular markers. However, molecular tools may present technical difficulties due to the masking of some alleles (allelic dropouts and/or null alleles), which tends to bias the estimation of heterozygosity and thus the inferences concerning the...
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