Article
Dabrafenib for the treatment of BRAF V600-positive melanoma: a safety evaluation.
Expert opinion on drug safety - 1 Sept 2014
Rutkowski Piotr, Blank Christian
Abstract excerpt
INTRODUCTION: V-raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibitors are emerging as the standard of care for treating advanced melanomas harboring the BRAF V600 oncogenic mutation. Dabrafenib is the second approved selective BRAF inhibitor (after vemurafenib) for the treatment of unresectable or metastatic BRAF V600-positive melanoma. AREAS COVERED: This review covers the current data on the efficacy...
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