Article
WDR72 models of structure and function: a stage-specific regulator of enamel mineralization.
Matrix biology : journal of the International Society for Matrix Biology - 1 Sept 2014
Katsura K A, Horst J A, Chandra D, Le T Q, Nakano Y, Zhang Y, Horst O V, Zhu L, Le M H, DenBesten P K
Abstract excerpt
Amelogenesis Imperfecta (AI) is a clinical diagnosis that encompasses a group of genetic mutations, each affecting processes involved in tooth enamel formation and thus, result in various enamel defects. The hypomaturation enamel phenotype has been described for mutations involved in the later stage of enamel formation, including Klk4, Mmp20, C4orf26, and Wdr72. Using a candidate gene approach we discovered a...
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