Article
Predictive role of CEA and CYFRA 21-1 in patients with advanced-stage NSCLC treated with erlotinib.
Anticancer research - 1 Jun 2014
Fiala Ondrej, Pesek Milos, Finek Jindrich, Benesova Lucie, Minarik Marek, Bortlicek Zbynek, Topolcan Ondrej
Abstract excerpt
BACKGROUND: Tumor biomarkers are used for predicting therapy effect and prognosis of patients with non-small cell lung cancer (NSCLC). We focused on their potential role in prediction of the efficacy of erlotinib. PATIENTS AND METHODS: In a total of 144 patients with advanced-stage (IIIB or IV) NSCLC treated with erlotinib, pre-treatment levels of soluble carcinoembryonic antigen (CEA) and cytokeratin markers in...
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