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Article

False-Positive Results in Metagenomic Virus Discovery: A Strong Case for Follow-Up Diagnosis

10 Jun 2014

Abstract excerpt

A viral metagenomic approach using virion enrichment, random amplification and next-generation sequencing was used to investigate an undiagnosed cluster of dairy cattle presenting with high persistent fever, unresponsive to anti-microbial and anti-inflammatory treatment, diarrhoea and redness of nose and teat. Serum and whole blood samples were taken in the predicted hyperviraemic state of an animal that a few...

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PMID: 24912559
DOI: 10.1111/tbed.12251

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