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Article

Exposure to Beta-(1,3)-D-glucan in house dust at age 7-10 is associated with airway hyperresponsiveness and atopic asthma by age 11-14.

PloS one - 1 Jan 2014

Maheswaran Dharini, Zeng Yiye, Chan-Yeung Moira, Scott James, Osornio-Vargas Alvaro, Becker Allan B, Kozyrskyj Anita L

Abstract excerpt

BACKGROUND: Mould exposure has been linked to childhood asthma and bronchial hyper-responsiveness. Few studies have assessed beta-(1,3)-d-glucan (beta-glucan), a significant fungal cell wall constituent, in relation to asthma in adolescence. OBJECTIVE: To determine whether house dust-derived beta-glucan exposure at age 7-10 is associated with the development and persistence of atopic and non-atopic asthma, and...

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Identifiers

PMID: 24905346
DOI: 10.1371/journal.pone.0098878
PMCID: PMC4048218

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