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Article

A RAS renaissance: emerging targeted therapies for KRAS-mutated non-small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2014

Vasan Neil, Boyer Julie L, Herbst Roy S

Abstract excerpt

Of the numerous oncogenes implicated in human cancer, the most common and perhaps the most elusive to target pharmacologically is RAS. Since the discovery of RAS in the 1960s, numerous studies have elucidated the mechanism of activity, regulation, and intracellular trafficking of the RAS gene pro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24893629
DOI: 10.1158/1078-0432.CCR-13-1762
PMCID: PMC5369356

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24893629-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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