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Article

microRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas

19 May 2014

Abstract excerpt

Burkitt lymphoma (BL) is a highly aggressive B-cell non-Hodgkin lymphoma (B-NHL), which originates from germinal center (GC) B cells and harbors translocations deregulating v-myc avian myelocytomatosis viral oncogene homolog (MYC). A comparative analysis of microRNAs expressed in normal and malignant GC B cells identified microRNA 28 (miR-28) as significantly down-regulated in BL, as well as in other GC-derived...

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PMID: 24843176
DOI: 10.1073/pnas.1322466111

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