Article
Genetic analyses of norovirus GII.4 variants in Finnish children from 1998 to 2013.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2014
Huhti Leena, Blazevic Vesna, Puustinen Leena, Hemming Maria, Salminen Marjo, Vesikari Timo
Abstract excerpt
Noroviruses (NoVs) are the major causative agents of acute gastroenteritis (AGE) in outbreaks and in sporadic AGE in young children. Since the mid-1990s, NoV genotype GII.4 has been predominant worldwide. New GII.4 variants appear every two to three years, and antigenic variation is focused on the highly variable protruding domain (P2) of the NoV capsid protein which contains the receptor-binding regions. We...
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