Article
Polymorphisms of the TNFAIP3 region and Graves' disease.
Autoimmunity - 1 Nov 2014
Song Rong-hua, Yu Zhi-yun, Wang Qiong, Muhali Fatuma-said, Jiang Wen-juan, Xiao Ling, Shi Xiao-hong, He Shuang-tao, Xu Jian, Zhang Jin-an
Abstract excerpt
Autoimmune thyroid disease (AITD) is a multifactorial organ-specific autoimmune disorder, and both genetic susceptibility and environmental factors are involved in its etiology. TNFAIP3 encodes the ubiquitin-modifying enzyme (A20), a key regulator of inflammatory signaling pathways. The aim of the present study was to evaluate the association between TNFAIP3 gene polymorphisms and AITD in Chinese Han population....
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