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Article

Circadian clock circuitry in colorectal cancer.

World journal of gastroenterology - 21 Apr 2014

Mazzoccoli Gianluigi, Vinciguerra Manlio, Papa Gennaro, Piepoli Ada

Abstract excerpt

Colorectal cancer is the most prevalent among digestive system cancers. Carcinogenesis relies on disrupted control of cellular processes, such as metabolism, proliferation, DNA damage recognition and repair, and apoptosis. Cell, tissue, organ and body physiology is characterized by periodic fluctuations driven by biological clocks operating through the clock gene machinery. Dysfunction of molecular clockworks and...

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Identifiers

PMID: 24764658
DOI: 10.3748/wjg.v20.i15.4197
PMCID: PMC3989956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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