Article
The role of interferon in the new era of hepatitis C treatments.
Expert review of gastroenterology & hepatology - 1 Aug 2014
Parekh Parth J, Shiffman Mitchell L
Abstract excerpt
Interferon has been the backbone of HCV treatment since this agent was first introduced nearly two decades ago. Interferon acts to eradicate HCV via two mechanisms: by directly inhibiting HCV replication via an indirect anti-viral mechanism and by modulating an immune response against hepatocytes infected with HCV. The current treatment of chronic HCV genotype 1 is the combination of peginterferon, ribavirin and...
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