Article
ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis.
The New England journal of medicine - 22 May 2014
Poordad Fred, Hezode Christophe, Trinh Roger, Kowdley Kris V, Zeuzem Stefan, Agarwal Kosh, Shiffman Mitchell L, Wedemeyer Heiner, Berg Thomas, Yoshida Eric M, Forns Xavier, Lovell Sandra S, Da Silva-Tillmann Barbara, Collins Christine A, Campbell Andrew L, Podsadecki Thomas, Bernstein Barry
Abstract excerpt
BACKGROUND: Interferon-containing regimens for the treatment of hepatitis C virus (HCV) infection are associated with increased toxic effects in patients who also have cirrhosis. We evaluated the interferon-free combination of the protease inhibitor ABT-450 with ritonavir (ABT-450/r), the NS5A in...
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