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Article

Suitability of IS6110-RFLP and MIRU-VNTR for differentiating spoligotyped drug-resistant mycobacterium tuberculosis clinical isolates from Sichuan in China.

BioMed research international - 1 Jan 2014

Zheng Chao, Zhao Yuding, Zhu Guoqiang, Li Song, Sun Honghu, Feng Qin, Luo Mei, Wu Fanzi, Li Xuefeng, Hill Véronique, Rastogi Nalin, Sun Qun

Abstract excerpt

Genotypes of Mycobacterium tuberculosis complex (MTBC) vary with the geographic origin of the patients and can affect tuberculosis (TB) transmission. This study was aimed to further differentiate spoligotype-defined clusters of drug-resistant MTBC clinical isolates split in Beijing (n = 190) versus non-Beijing isolates (n = 84) from Sichuan region, the second high-burden province in China, by IS6110-restriction...

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Identifiers

PMID: 24724099
DOI: 10.1155/2014/763204
PMCID: PMC3958788

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