Article
Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents.
Journal of clinical microbiology - 1 Jun 2014
Zhao Yanan, Armeanu Emilian, DiVerniero Richard, Lewis Terri A, Dobson Richard C, Kontoyiannis Dimitrios P, Roilides Emmanuel, Walsh Thomas J, Perlin David S
Abstract excerpt
Using Exserohilum rostratum-specific and panfungal real-time PCR, we studied 24 blood samples and 2 synovial fluid specimens from 20 patients with persistent or worsening pain following injections of contaminated methylprednisolone. Seven blood specimens from 6 patients were significantly positive for fungal DNA by panfungal PCR, with multiple fungal species identified.
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