Article
Functional study of a genetic marker allele associated with resistance to Ascaris suum in pigs.
Parasitology - 1 May 2014
Skallerup Per, Thamsborg Stig M, Jørgensen Claus B, Enemark Heidi L, Yoshida Ayako, Göring Harald H H, Fredholm Merete, Nejsum Peter
Abstract excerpt
Two single nucleotide polymorphisms (SNP TXNIP and SNP ARNT), both on chromosome 4, have been reported to be associated with roundworm (Ascaris suum) burden in pigs. In the present study, we selected pigs with two SNP TXNIP genotypes (AA; n = 24 and AB; n = 24), trickle-infected them with A. suum from 8 weeks of age until necropsy 8 weeks later, and tested the hypothesis that pigs with the AA genotype would have...
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