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RNAi-Mediated Gene Silencing in a Gonad Organ Culture to Study Sex Determination Mechanisms in Sea Turtle

7 Jun 2013

Abstract excerpt

The autosomal Sry-related gene, Sox9, encodes a transcription factor, which performs an important role in testis differentiation in mammals. In several reptiles, Sox9 is differentially expressed in gonads, showing a significant upregulation during the thermo-sensitive period (TSP) at the male-promoting temperature, consistent with the idea that SOX9 plays a central role in the male pathway. However, in spite of...

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PMID: 24705165
DOI: 10.3390/genes4020293

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RNAi-Mediated Gene Silencing in a Gonad Organ Culture to Study Sex Determination Mechanisms in Sea TurtlePMID 24705165Read ↗

Expression of Putative Sex-Determining Genes during the Thermosensitive Period of Gonad Development in the Snapping Turtle, <i>Chelydra serpentina</i>Semantic proximity Read ↗

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Temperature-dependent sex determination: Upregulation ofSOX9 expression after commitment to male developmentSemantic proximity Read ↗

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Temperature Regulates SOX9 Expression in Cultured Gonads of Lepidochelys olivacea, a Species with Temperature Sex DeterminationSemantic proximity Read ↗

The Role of Anti-Müllerian Hormone in Testis Differentiation Reveals the Significance of the TGF-β Pathway in Reptilian Sex Determination.Semantic proximity Read ↗

Chronology, Magnitude and Duration of Expression of Putative Sex-Determining/Differentiation Genes in a Turtle with Temperature-Dependent Sex DeterminationSemantic proximity Read ↗

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Expression of <i>Sox9</i>, <i>Mis</i>, and <i>Dmrt1</i> in the gonad of a species with temperature‐dependent sex determinationSemantic proximity Read ↗

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