Article
Experimental infections with Mycoplasma agalactiae identify key factors involved in host-colonization.
PloS one - 1 Jan 2014
Baranowski Eric, Bergonier Dominique, Sagné Eveline, Hygonenq Marie-Claude, Ronsin Patricia, Berthelot Xavier, Citti Christine
Abstract excerpt
Mechanisms underlying pathogenic processes in mycoplasma infections are poorly understood, mainly because of limited sequence similarities with classical, bacterial virulence factors. Recently, large-scale transposon mutagenesis in the ruminant pathogen Mycoplasma agalactiae identified the NIF locus, including nifS and nifU, as essential for mycoplasma growth in cell culture, while dispensable in axenic media. To...
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