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Studying the System-Level Involvement of MicroRNAs in Parkinson's Disease

1 Apr 2014

Abstract excerpt

BACKGROUND: Parkinson's Disease (PD) is a progressive neurologic disorder that affects movement and balance. Recent studies have revealed the importance of microRNA (miR) in PD. However, the detailed role of miR and its regulation by Transcription Factor (TF) remain unexplored. In this work for the first time we have studied TF-miR-mRNA regulatory network as well as miR co-expression network in PD. RESULT: We...

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PMID: 24690883
DOI: 10.1371/journal.pone.0093751

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