Article
Active Learning Strategies for Phenotypic Profiling of High-Content Screens.
Journal of biomolecular screening - 1 Jun 2014
Smith Kevin, Horvath Peter
Abstract excerpt
High-content screening is a powerful method to discover new drugs and carry out basic biological research. Increasingly, high-content screens have come to rely on supervised machine learning (SML) to perform automatic phenotypic classification as an essential step of the analysis. However, this comes at a cost, namely, the labeled examples required to train the predictive model. Classification performance...
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