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Article

A classical genetic solution to enhance the biosynthesis of anticancer phytochemicals in Andrographis paniculata Nees.

PloS one - 1 Jan 2014

Valdiani Alireza, Talei Daryush, Tan Soon Guan, Abdul Kadir Mihdzar, Maziah Mahmood, Rafii Mohd Yusop, Sagineedu Sreenivasa Rao

Abstract excerpt

Andrographolides, the diterpene lactones, are major bioactive phytochemicals which could be found in different parts of the medicinal herb Andrographis paniculata. A number of such compounds namely andrographolide (AG), neoandrographolide (NAG), and 14-deoxy-11,12-didehydroandrographolide (DDAG) have already attracted a great deal of attention due to their potential therapeutic effects in hard-to-treat diseases...

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Identifiers

PMID: 24586262
DOI: 10.1371/journal.pone.0087034
PMCID: PMC3934858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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