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Article

Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer.

Medical hypotheses - 1 Apr 2014

Bhargava Shiva

Abstract excerpt

Androgenic alopecia, a condition characterized by increased levels of DHT could have been selected for due to the benefits that prostaglandin D2 (PGD(2)) has on the prostate. A DHT metabolite can increase the transcription of prostaglandin D2 synthase through estrogen receptor beta. The increase...

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Source

Identifiers

PMID: 24548754
DOI: 10.1016/j.mehy.2014.01.016

Genes

PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24548754-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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