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Article

Risk of death in heart disease is associated with elevated urinary globotriaosylceramide.

Journal of the American Heart Association - 4 Feb 2014

Schiffmann Raphael, Forni Sabrina, Swift Caren, Brignol Nastry, Wu Xiaoyang, Lockhart David J, Blankenship Derek, Wang Xuan, Grayburn Paul A, Taylor Matthew R G, Lowes Brian D, Fuller Maria, Benjamin Elfrida R, Sweetman Lawrence

Abstract excerpt

BACKGROUND: Elevated urinary globotriaosylceramide (Gb3) has been considered a hallmark of Fabry disease, an X-linked lysosomal disorder that is a risk factor for most types of heart disease. METHODS AND RESULTS: We screened 1421 consecutive patients with common forms of heart disease for Fabry d...

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Identifiers

PMID: 24496231
DOI: 10.1161/JAHA.113.000394
PMCID: PMC3959711

Genes

GLA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-24496231-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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