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Article

Rapid selection of sperm with high DNA integrity

1 Jan 2014

Abstract excerpt

Sperm selection is essential to assisted reproductive technology (ART), influencing treatment outcomes and the health of offspring. The fundamental challenge of sperm selection is dictated by biology: a heterogeneous population of ~10(8) sperm per milliliter with a short lifetime in vitro. However, conventional sperm selection approaches result in less than 50% improvement in DNA integrity. Here, a clinically...

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PMID: 24464038
DOI: 10.1039/c3lc51254a

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