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Control of plant defense mechanisms and fire blight pathogenesis through the regulation of 6-thioguanine biosynthesis in Erwinia amylovora.

Chembiochem : a European journal of chemical biology - 10 Feb 2014

Coyne Sébastien, Litomska Agnieszka, Chizzali Cornelia, Khalil Mohammed N A, Richter Klaus, Beerhues Ludger, Hertweck Christian

Abstract excerpt

Fire blight is a devastating disease of Rosaceae plants, such as apple and pear trees. It is characterized by necrosis of plant tissue, caused by the phytopathogenic bacterium Erwinia amylovora. The plant pathogen produces the well-known antimetabolite 6-thioguanine (6TG), which plays a key role in fire blight pathogenesis. Here we report that YcfR, a member of the LTTR family, is a major regulator of 6TG...

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Bacterial Outer Membrane Proteins
Benzofurans
Biphenyl Compounds
Multigene Family
Plant Cells

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PMID: 24449489
DOI: 10.1002/cbic.201300684

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Control of plant defense mechanisms and fire blight pathogenesis through the regulation of 6-thioguanine biosynthesis in Erwinia amylovora.PMID 24449489Read ↗

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