Article
Direct estimates of natural selection in Iberia indicate calcium absorption was not the only driver of lactase persistence in Europe.
Molecular biology and evolution - 1 Apr 2014
Sverrisdóttir Oddny Ósk, Timpson Adrian, Toombs Jamie, Lecoeur Cecile, Froguel Philippe, Carretero Jose Miguel, Arsuaga Ferreras Juan Luis, Götherström Anders, Thomas Mark G
Abstract excerpt
Lactase persistence (LP) is a genetically determined trait whereby the enzyme lactase is expressed throughout adult life. Lactase is necessary for the digestion of lactose--the main carbohydrate in milk--and its production is downregulated after the weaning period in most humans and all other mammals studied. Several sources of evidence indicate that LP has evolved independently, in different parts of the world...
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