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Article

Influence of Acanthamoeba genotype on clinical course and outcomes for patients with Acanthamoeba keratitis in Spain.

Journal of clinical microbiology - 1 Apr 2014

Arnalich-Montiel Francisco, Lumbreras-Fernández Blanca, Martín-Navarro Carmen M, Valladares Basilio, Lopez-Velez Rogelio, Morcillo-Laiz Rafael, Lorenzo-Morales Jacob

Abstract excerpt

Genotype T4 is by far the most frequent genotype of Acanthamoeba keratitis (AK) and therefore has been considered the most virulent. This study included 14 cases of AK of genotype T4 and three cases of non-T4 genotype. We found that cases of non-T4 genotype had a worse response to medical therapy, greater need for surgical intervention, greater risk of extracorneal involvement, and remarkably poorer final visual...

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Identifiers

PMID: 24430449
DOI: 10.1128/JCM.00031-14
PMCID: PMC3993498

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