Article
Identification of a novel membrane transporter mediating resistance to organic arsenic in Campylobacter jejuni.
Antimicrobial agents and chemotherapy - 1 Jan 2014
Shen Zhangqi, Luangtongkum Taradon, Qiang Zhiyi, Jeon Byeonghwa, Wang Liping, Zhang Qijing
Abstract excerpt
Although bacterial mechanisms involved in the resistance to inorganic arsenic are well understood, the molecular basis for organic arsenic resistance has not been described. Campylobacter jejuni, a major food-borne pathogen causing gastroenteritis in humans, is highly prevalent in poultry and is reportedly resistant to the arsenic compound roxarsone (4-hydroxy-3-nitrobenzenearsonic acid), which has been used as a...
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