Article
Infectious bursal disease virus influences the transcription of chicken γc and γc family cytokines during infection.
PloS one - 1 Jan 2014
Wang Sanying, Teng Qiaoyang, Jia Lu, Sun Xiaoyuan, Wu Yongping, Zhou Jiyong
Abstract excerpt
Infectious bursal disease virus (IBDV) infection causes immunodeficiency in chickens. To understand cell-mediated immunity during IBDV infection, this study perform a detailed analysis of chicken γc chain (chCD132) and γc family cytokines, including interleukins 2, 4, 7, 9, and 15. The mouse anti-chCD132 monoclonal antibody (mAb) was first generated by the E.coli-expressed γc protein. Immunofluorescence assay...
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