Article
Factors associated with early progression of non-small-cell lung cancer treated by epidermal growth factor receptor tyrosine-kinase inhibitors.
Cancer medicine - 1 Feb 2014
Rozensztajn Nathalie, Ruppert Anne-Marie, Lavole Armelle, Leprieur Etienne Giroux, Duruisseaux Michael, Vieira Thibault, Rabbe Nathalie, Lacave Roger, Antoine Martine, Cadranel Jacques, Wislez Marie
Abstract excerpt
Epidermal growth factor receptor tyrosine-kinase inhibitors (EGFR-TKI) are a therapeutic option as second-line therapy in non-small-cell lung carcinoma (NSCLC), regardless of the EGFR gene status. Identifying patients with early progression during EGFR-TKI treatment will help clinicians to choose the best regimen, TKI or chemotherapy. From a prospective database, all patients treated with gefitinib or erlotinib...
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