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Article

Genome-based approaches to develop epitope-driven subunit vaccines against pathogens of infective endocarditis

19 Jun 2013

Abstract excerpt

Infective endocarditis (IE) has emerged as a public health problem due to changes in the etiologic spectrum and due to involvement of resistant bacterial strains with increased virulence. Developing potent vaccine is an important strategy to tackle IE. Complete genome sequences of eight selected pathogens of IE paved the way to design common T-cell driven subunit vaccines. Comparative genomics and subtractive...

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PMID: 24404767
DOI: 10.1080/07391102.2013.795871

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