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Deregulated micro<scp>RNA</scp>s in <scp>CD</scp>4<sup>+</sup> T cells from individuals with latent tuberculosis <i>versus</i> active tuberculosis

25 Dec 2013

Abstract excerpt

The mechanisms of latent tuberculosis (TB) infection remain elusive. Roles of microRNA (miRNA) have been highlighted in pathogen-host interactions recently. To identify miRNAs involved in the immune response to TB, expression profiles of miRNAs in CD4(+) T cells from patients with latent TB, active TB and healthy controls were investigated by microarray assay and validated by RT-qPCR. Gene ontology (GO) and Kyoto...

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PMID: 24373112
DOI: 10.1111/jcmm.12205

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