Faster-X adaptive protein evolution in house mice.

doi:10.1534/genetics.113.158246

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Article

Faster-X adaptive protein evolution in house mice.

Genetics - 1 Apr 2014

Kousathanas Athanasios, Halligan Daniel L, Keightley Peter D

Abstract excerpt

The causes of the large effect of the X chromosome in reproductive isolation and speciation have long been debated. The faster-X hypothesis predicts that X-linked loci are expected to have higher rates of adaptive evolution than autosomal loci if new beneficial mutations are on average recessive. Reproductive isolation should therefore evolve faster when contributing loci are located on the X chromosome. In this...

Topics

Animals
Chromosomes, Mammalian
Evolution, Molecular
Female
Genes, X-Linked
Genetic Speciation
Genetic Variation
Genome
Humans
Male
Mice
Murinae
Phylogeny
Polymorphism, Single Nucleotide
Rats
Spermatogenesis
X Chromosome
X Chromosome Inactivation

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Identifiers

PMID: 24361937
DOI: 10.1534/genetics.113.158246
PMCID: PMC3982706

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