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Article

MiR-181c modulates the proliferation, migration, and invasion of neuroblastoma cells by targeting Smad7

18 Dec 2013

Abstract excerpt

MicroRNAs (miRNAs) function as key regulators of gene expression in various cancers. In this study, the aim is to explore the roles and regulation mechanism of miR-181c in neuroblastoma (NB) cells. We found that miR-181c was downregulated in metastatic NB tissues, compared with primary NB tissues. Then functional studies indicated that miR-181c overexpression inhibited NB cell proliferation, migration, and...

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PMID: 24345480
DOI: 10.1093/abbs/gmt124

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