Article
miR-329 suppresses the growth and motility of neuroblastoma by targeting KDM1A.
FEBS letters - 3 Jan 2014
Yang Haifeng, Li Qi, Zhao Wohua, Yuan Dun, Zhao Hongyang, Zhou Yong
Abstract excerpt
MicroRNAs (miRNAs) act as key regulators of multiple cancers. miR-329 functions as a tumor suppressor in some malignancies. However, its role in neuroblastoma remains poorly understood. We found that miR-329 was decreased in metastatic tumor tissues compared with matched primary tumor tissues. Forced overexpression of miR-329 substantially suppressed cell proliferation, colony formation, migration, and invasion...
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