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Host-Directed Therapeutics for Tuberculosis: Can We Harness the Host?

1 Dec 2013

Abstract excerpt

Treatment of tuberculosis (TB) remains challenging, with lengthy treatment durations and complex drug regimens that are toxic and difficult to administer. Similar to the vast majority of antibiotics, drugs for Mycobacterium tuberculosis are directed against microbial targets. Although more effective drugs that target the bacterium may lead to faster cure of patients, it is possible that a biological limit will be...

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PMID: 24296574
DOI: 10.1128/mmbr.00032-13

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