Article
Interleukin 28B gene polymorphisms in hepatitis C virus-related cryoglobulinemic vasculitis.
The Journal of rheumatology - 1 Jan 2014
Sansonno Domenico, Russi Sabino, Serviddio Gaetano, Conteduca Vincenza, D'Andrea Giovanna, Sansonno Loredana, Pavone Fabio, Lauletta Gianfranco, Mariggiò Maria Addolorata, Dammacco Franco
Abstract excerpt
OBJECTIVE: Single-nucleotide polymorphisms (SNP) in the interleukin 28B (IL-28B) gene region are strongly predictive of the response of infected patients to antiviral therapy for hepatitis C virus (HCV). We sought to determine the prevalence of SNP IL-28B rs12979860 C/C and non-C/C (C/T plus T/T) genotypes in HCV-related cryoglobulinemic vasculitis (CV), as compared with HCV-positive patients without CV. We also...
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