Article
Genetic mutations in influenza H3N2 viruses from a 2012 epidemic in Southern China.
Virology journal - 26 Nov 2013
Zhong Jing, Liang Lijun, Huang Ping, Zhu Xiaolan, Zou Lirong, Yu Shouyi, Zhang Xin, Zhang Yonghui, Ni Hanzhong, Yan Jin
Abstract excerpt
BACKGROUND: An influenza H3N2 epidemic occurred throughout Southern China in 2012. METHODS: We analyzed the hemagglutinin (HA) and neuraminidase (NA) genes of influenza H3N2 strains isolated between 2011-2012 from Guangdong. Mutation sites, evolutionary selection, antigenic sites, and N-glycosylation within these strains were analyzed. RESULTS: The 2011-2012 Guangdong strains contained the HA-A214S, HA-V239I,...
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