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Article

Replacement and positive evolution of subtype A and B respiratory syncytial virus G-protein genotypes from 1997-2012 in South Africa.

The Journal of infectious diseases - 15 Dec 2013

Pretorius Marthi A, van Niekerk Stephanie, Tempia Stefano, Moyes Jocelyn, Cohen Cheryl, Madhi Shabir A, Venter Marietjie

Abstract excerpt

BACKGROUND: Of the respiratory syncytial virus (RSV) genotypes previously described in South Africa during 1997-2002, only GA2 and GA5 persisted until 2006, with BA having replaced all previous RSV-B genotypes. This poses the question whether RSV-A is more stable than RSV-B and whether positive selection drives evolution of genotypes. METHODS: RSV-positive specimens were randomly selected during 2009-2012,...

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PMID: 24265482
DOI: 10.1093/infdis/jit477

Genes

SAA2

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