Article
Load-sensitive coupling of proton translocation and torque generation in the bacterial flagellar motor.
Molecular microbiology - 1 Jan 2014
Che Yong-Suk, Nakamura Shuichi, Morimoto Yusuke V, Kami-Ike Nobunori, Namba Keiichi, Minamino Tohru
Abstract excerpt
The Salmonella flagellar motor consists of a rotor and about a dozen stator elements. Each stator element, consisting of MotA and MotB, acts as a proton channel to couple proton flow with torque generation. A highly conserved Asp33 residue of MotB is directly involved in the energy coupling mechanism, but it remains unknown how it carries out this function. Here, we show that the MotB(D33E) mutation dramatically...
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