Article
Rapid differentiation between livestock-associated and livestock-independent Staphylococcus aureus CC398 clades.
PloS one - 1 Jan 2013
Stegger Marc, Liu Cindy M, Larsen Jesper, Soldanova Katerina, Aziz Maliha, Contente-Cuomo Tania, Petersen Andreas, Vandendriessche Stien, Jiménez Judy N, Mammina Caterina, van Belkum Alex, Salmenlinna Saara, Laurent Frederic, Skov Robert L, Larsen Anders R, Andersen Paal S, Price Lance B
Abstract excerpt
Staphylococcus aureus clonal complex 398 (CC398) isolates cluster into two distinct phylogenetic clades based on single-nucleotide polymorphisms (SNPs) revealing a basal human clade and a more derived livestock clade. The scn and tet(M) genes are strongly associated with the human and the livestock clade, respectively, due to loss and acquisition of mobile genetic elements. We present canonical single-nucleotide...
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