Article
Flagellin and F4 fimbriae have opposite effects on biofilm formation and quorum sensing in F4ac+ enterotoxigenic Escherichia coli.
Veterinary microbiology - 10 Jan 2014
Zhou Mingxu, Guo Zhiyan, Yang Yang, Duan Qiangde, Zhang Qi, Yao Fenghua, Zhu Jun, Zhang Xinjun, Hardwidge Philip R, Zhu Guoqiang
Abstract excerpt
Bacteria that form biofilms are often highly resistant to antibiotics and are capable of evading the host immune system. To evaluate the role of flagellin and F4 fimbriae on biofilm formation by enterotoxigenic Escherichia coli (ETEC), we deleted the fliC (encoding the major flagellin protein) and/or the faeG (encoding the major subunit of F4 fimbriae) genes from ETEC C83902. Biofilm formation was reduced in the...
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