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Article

Plasma miRNAs as Diagnostic and Prognostic Biomarkers for Ovarian Cancer

1 Nov 2013

Abstract excerpt

BACKGROUND: Most (70%) epithelial ovarian cancers (EOCs) are diagnosed late. Non-invasive biomarkers that facilitate disease detection and predict outcome are needed. The microRNAs (miRNAs) represent a new class of biomarkers. This study was to identify and validate plasma miRNAs as biomarkers in EOC. METHODOLOGY/PRINCIPAL FINDINGS: We evaluated plasma samples of 360 EOC patients and 200 healthy controls from two...

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PMID: 24223734
DOI: 10.1371/journal.pone.0077853

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