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Article

Biosynthesis and Mass Spectrometric Imaging of Tolaasin, the Virulence Factor of Brown Blotch Mushroom Disease

12 Nov 2013

Abstract excerpt

Killing them softly. The molecular basis for the biosynthesis of tolaasin, the Pseudomonas tolaasii-derived causative agent of mushroom (Agaricus bisporus) soft rot, was revealed by genome mining and analysis of the NRPS genes. Production of the toxic lipopeptides during infection was confirmed by imaging mass spectrometry.

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PMID: 24222604
DOI: 10.1002/cbic.201300553

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