Article
Positive selection and evolution of dengue type-3 virus in the Indian subcontinent.
Journal of vector borne diseases - 1 Sept 2013
Bedi Sukhmani K, Prasad Apar, Mathur Krishanu, Bhatnagar Sonika
Abstract excerpt
BACKGROUND: Dengue virus infection has recently taken endemic proportions in India with dengu type-3 (DEN-3) as a predominant serotype. In this study, we carried out the selection pressure analysis of three critical immunogenic regions of DEN-3. Phylogenetic analysis was then carried out on the positively selected genomic region in the DEN-3 virus strains isolated in the Indian subcontinent over a time span of 25...
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