Article
Genomic evolution of the pathogenic Wolbachia strain, wMelPop.
Genome biology and evolution - 1 Jan 2013
Woolfit Megan, Iturbe-Ormaetxe Iñaki, Brownlie Jeremy C, Walker Thomas, Riegler Markus, Seleznev Andrei, Popovici Jean, Rancès Edwige, Wee Bryan A, Pavlides Jennifer, Sullivan Mitchell J, Beatson Scott A, Lane Amanda, Sidhu Manpreet, McMeniman Conor J, McGraw Elizabeth A, O'Neill Scott L
Abstract excerpt
Most strains of the widespread endosymbiotic bacterium Wolbachia pipientis are benign or behave as reproductive parasites. The pathogenic strain wMelPop is a striking exception, however: it overreplicates in its insect hosts and causes severe life shortening. The mechanism of this pathogenesis is currently unknown. We have sequenced the genomes of three variants of wMelPop and of the closely related nonpathogenic...
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