Article
Effect of Kampo medicine "Dai-kenchu-to" on microbiome in the intestine of the rats with fast stress.
The journal of medical investigation : JMI - 1 Jan 2013
Yoshikawa Kozo, Shimada Mitsuo, Kuwahara Tomomi, Hirakawa Hideki, Kurita Nobuhiro, Sato Hirohiko, Utsunomiya Tohru, Iwata Takashi, Miyatani Tomohiko, Higashijima Jun, Kashihara Hideya, Takasu Chie, Matsumoto Noriko, Nakayama-Imaohji Haruyuki
Abstract excerpt
PURPOSE: Diversity of gut microbiome has been recently reported to be lost in inflammatory bowel disease. We have previously reported that the Dai-kenchu-to (DKT) prevented the bacterial translocation through suppression of cytokine and apoptosis in rat's fast stress model. The aim of this study was to evaluate the effect of DKT on maintenance of microbial diversity in rat's intestine with inflammation. METHOD:...
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