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Article

Microdeletion and microduplication analysis of chinese conotruncal defects patients with targeted array comparative genomic hybridization.

PloS one - 1 Jan 2013

Gong Xiaohui, Wu Xi, Ma Xiaojing, Wu Dandan, Zhang Ting, He Li, Qin Shengying, Li Xiaotian

Abstract excerpt

OBJECTIVE: The current study aimed to develop a reliable targeted array comparative genomic hybridization (aCGH) to detect microdeletions and microduplications in congenital conotruncal defects (CTDs), especially on 22q11.2 region, and for some other chromosomal aberrations, such as 5p15-5p, 7q11.23 and 4p16.3. METHODS: Twenty-seven patients with CTDs, including 12 pulmonary atresia (PA), 10 double-outlet right...

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Identifiers

PMID: 24098474
DOI: 10.1371/journal.pone.0076314
PMCID: PMC3788710

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