Telaprevir-induced, but not pegylated interferon-associated, retinopathy as a noteworthy adverse effect during triple antiviral therapy in patients with chronic hepatitis C.

Abstract excerpt

BACKGROUND: The significance of retinopathy during triple therapy with telaprevir is uncertain. METHODS: Ophthalmologic examination was done prospectively before and every month during the therapy in 95 CHC patients. RESULTS: Retinopathy was found in 46 (48.4 %), and the specialists recommended discontinuation of the therapy in 9 (9.5 %). Such lesions may develop as adverse effects by telaprevir, since the...

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